Yes. More then 99% of all supplements sold are synthetic. They are typically one version of one or more particular vitamins. In food, vitamins have many versions or structural configurations that work together like the instruments of a symphony. Alone, they can cause a number of issues including upset stomach, nausea, gas, headaches, and worse. However together in their natural variations and combinations that are only found in a whole food based supplement, they provide the millions of cells of the body with what they need to function at their peak. When your body has the materials it needs, it works. Our supplements combined with good food allow that to happen.